Adding in my two cents as well:
I also suspect that this is a much more prevalent issue than what is being reported - just simply most users experiencing this issue haven't figured out (yet) that it's malwarebytes causing the issue. Speaking from personal experience, I had 1 system that's been locking up intermittently since around December 13th, and the 2nd system just started locking up about a week ago. Both sets of hardware are pretty near polar opposites of one another.
It's taken me all this time to figure out that it was malwarebytes in both cases. The 1st system - has completely been through the ringer (tested all of the hardware from the power supply all the way to the motherboard; also found corrupted windows files that could not be repaired - so it's a clean install). The 2nd system - I thought it was windows registry issues - so to has a clean install.
Long story short - I'm baffled by what's causing the issue, but using the trick of disabling web &/or ransomware protection has resulted in zero lockups.