System: Dell XPS 8700, Windows 10 Pro 64 bit, version 1803. Windows Defender, Malwarebytes 3 Premium, all current. I am hearing from serious and credible Windows experts that it's unwise to have more than one program at a time doing real-time scanning, because of possible interference. They are saying use MB as on-demand scanner, but don't activate the real--time detection features. So I am asking what to think of this advice, and for an explanation (as technical as may be necessary) for why MB will not interfere with Windows Defender (and vice versa), and/or what precautions are advisable to prevent interference from occurring.
I have previously run MB alongside Avast Premier without observable problems. I did have problems with a newly installed UHD monitor (blackouts, system freezes etc.). Some thought that MB and/or Avast were responsible. That seems not to have been the case; removing CCleaner Pro seems to have solved that problem.
I cannot claim to be a Windows expert, or a security expert, but I've been in computers for a long time (since before they were electronic), written software (mostly database apps) in mainframe and PC environments, built and maintained corporate networks, etc., so I might be able to understand an explanation of how MB avoids interfering with Windows Defender (etc.), if that is indeed the case. And of course I also understand confidentiality limitations.
Thanks for any enlightenment you can provide.