The same odd thing started happening to me a few days ago, for no reason I could think of. I also got the Anti-Virus 2010 infection about 2 months ago. The WORST virus I had ever seen...totally locked my computer. Fortunately, I had another system available and was able to do some research...that's when I started using a fully licensed version of Malware Bytes. I also use Microsoft Security Essentials (free). A safe mode boot let me do a system restore. Then, I installed MB, which got the infected items out. Then following advice from MB forums I went in and manually deleted remnants of Anti-Virus. Now I'm a fanatic about updating the profiles and scanning every download. So, back to all these blocks coming up. Are you a multiplayer gamer? I play COD4 and get MB rejects from some of the servers. Sometimes blocked servers keep pinging, even after the game is off (some feature must not shut down until a reboot). Anyhow, I recognize the COD4 MB blocks. But for a few days it's been doing exactly as you said, creating *lots* of popups with addresses that aren't obviously linked to websites. Just random seeming IPs. In my case, it was BitTorrent. I reinstalled it the other day on a whim and forgot to change the preference so it does NOT start up by itself. I killed BT and now the blocks have stopped. You say you don't have any P2P but with all the crap software out there that "calls home" you should take another look. I reinstalled BT on a whim and forgot about it. Sounds like your problem is something simple along these lines. But it never hurts to be paranoid when it comes to viruses! (-;