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Vista Home and virus removal

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When I try to run Malware Bytes or Hijack This, I get an error message.

"Windows cannot access the specified device path or file, You may not have the appropriate permissions to access the item"

Running Vista Home.

Logged in as Administrator and UAC turned off.

Windows Defender found a few things as did Combofix.

I have installed AVAST A/V it did a boot scan and found 3 items but it will not run correctly when Vista loads.

I there a solution to this problem?

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Hello, and welcome to Malwarebytes.org

We don't work on Malware removal in the general forums.

Please print out, read and follow the directions here, skipping any steps you are unable to complete. Then post a NEW topic here.

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Alternatively, as a paying customer, you can contact the help desk at support@malwarebytes.org

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