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cant run mbam or spybot get access denied

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hi recently started to have problems with my computer and spywear detection as i can no longer scan or open them as when i try i get a message saying "windows cannot access specified device, path or file. you may not have appropriate permesion to access items." tried to run as administration on vista as i have the administraters profile and still getting the same problem.

i tried to run hijackthis and the same error appeared and i can no longer reinstall it so i could not get a hijackthis log but i have got a Win32Diag log attached below


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Due to the lack of feedback this Topic is closed to prevent others from posting here. If you need this topic reopened, please send a Private Message to any one of the moderating team members. Please include a link to this thread with your request. This applies only to the originator of this thread.

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The fixes and advice in this thread are for this machine only. Do not apply the instructions from this thread to your own machine. Please start a new thread describing your issue and someone will be along to assist you.

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