Removing PUPs: Negative Consequences?

[TooManyPUPS]

My scan completed with 1544 PUPs detected. Its a work computer and my co-workers and supervisor are reluctant to remove or quarantine so many files (they are all marked as PUPs). Are there any potentially harmful consequences to quarantining PUPs (especially so many)? For example, are there files, keys, processes, etc. that Malwarebytes considers PUPs that are essential to the functionality of commonly accepted programs (browsers and such)? Sorry if this is an inappropriate forum for this topic--please direct me to where this post would be best received and I will move it asap, if necessary.  

[TooManyPUPS]

Here are the scan logs

MBAM-log-2016-07-15 (15-34-35).txt

[AdvancedSetup]

Hello  @TooManyPUPS and

In looking at the log they look like valid detections to me. You can reset Chrome and that will remove most of them by doing so if you like.

 

 

I would like to reset Chrome back to defaults to completely clear out what is going on with Chrome.

You can keep your “Bookmarks” if you want to keep them, but you have to export them first – >> Export Bookmarks << – Everything else should be removed.

Then I need you to go to >> Google Sync << and sign into your account.
Scroll down until you see the “reset sync” button and click on the button
At the prompt click on “Ok”.

.
Reset Your Browser Settings
.

1. In the top-right corner of the browser window, click the “Chrome Menu” icon (Three horizontal lines)
2. Select “Settings”.
3. At the bottom, click “Show advanced settings…”
4. Scroll down until you see “Reset settings”, Then click on the button “Reset Settings”.
5. In the dialog that appears, click “Reset”.

.
Close Chrome and restart it and check it out for me please

Then restart the computer and run a new MBAM scan and post back the new log.