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Administrator denied access to delete possible malware. Hacked?

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I am fearful that I might be infected.

When I Autoruns at Sysinternals it shows to items which are concerning as I cannot delete them even when I try to do so as an Administrator.

MpFilter Microsoft On-Access Malware Protection Mini-Filter Driver File not found: system32\DRIVERS\MpFilter.sys

NisDrv NIS helps guard against intrusion attempts targeting known and newly discovered vulnerabilities in network protocols File not found: system32\DRIVERS\NisDrvWFP.sys

I would like to find out how to delete these and if I am infected or have been hacked.

Thank you

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1PW: Did I do something wrong in posting this request? If so, I apologize to the Group.

Your profile says: "Spam Hunters."

If the implication of your comment is that I am indulging in "Spam" may I heartily assure you that my question is being asked in good faith and I am innocent of perpetuating "Spam" in any manner.

Thank you.

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