I have been seeing this problem with the last two versions of Malwarebytes. I clean 2-3 xp/win7 machines a week, different companies different domains and some home users. Log in as local admin, run malwarebytes and everything is fine - icons and .exe's work. But I need to log in as each user and run multiple reg fixes for file associations and icons. At first I thought it was the spyware but this is happening in EVERY case there are multiple users on a pc. Been using Malwarebytes for years as a cleanup tool and this issue has just started recently. It looks like the only user not affected is the one I run the inital repair on.