Had the exact same issues running the windows 10 2004 insider build with premium 4.1 , the solution at the current time is to roll back to Malwarebytes 3.8.3.2965 and ensure system software update is switched off in settings , keep on this version until MWB can identify the issue , it bugged me for weeks , but then found a post offering this solution , everything has been running full tilt on the old V3 premium no problem , but windows 10 2004 and V4.1 seem to clash. link to download the old version , making sure auto updates are switched off. Hope this helps