I don't mean to bring back what seems to be a dead thread, but I just bought the ITNS-500 today at a Goodwill and it's working perfectly on Windows 10.
Mine luckily had every single part including the installation disc. All I did was used device manager to detect the scanner and automatically install the appropriate drivers--no compatibility issues whatsoever. Despite this, the scans are kinda awful, and one might as well get a better scanner if they are serious about their film scans.
Here is an image straight from the scanner without any editing. Even if I cleaned it up a bit and adjusted the film for the bottom right light imbalance, the dynamic range of the scanner seems to be pretty terrible.
Here's a comparable "professional" scan. Granted, this is an awful example considering that it's a bit hazy and the lighting is kinda terrible too.