Im testing AdwCleaner on a virtual machine and while testing I discovered that AdwCleaner seems to detect PUP.OptionAdwCleaner[S03].txtal.DriverSupport rightfully, but it cant delete it.
It detects the Folder "C:\ProgramData\UAB" and the Registry Key "HKLM\Software\Wow6432Node\ActiveOptimization", but fails to detect the Programs main directory (C:\Program Files (x86)\Driver Support) and its second directory (C:\ProgramData\DriverSupport). It therefore fails to remove DriverSupport. I dont think this has something to do with AdwCleaner running on a virtual machine, but rather that it just doesn't detect the PUP right. I can give you a setup of DriverSupport and the download link if needed. I have attached the scan log.