When I updated from my old Malwarebytes version to 3.0 I noticed a significant general performance impact on my computer.
Nothing major, but everything feels slow and unstable. Just loading up Explorer and Task Manager in Windows 10 takes a little longer than usual after Malwarebytes 3.0. Almost feels a little bit like I'm back on an old traditional physical hard drive when in fact I'm using a Samsung EVO 850 SSD as my primary drive.
Applications like games is not affected, but programs like Firefox, Photoshop and Sony Vegas take a little while to load up even on an SSD.
Running Malwarebytes 3.0 in combination with Avast as I have always done, and I'm on WIndows 10 Home 64-bit, (i5-6600K, 16GB RAM, GTX 1070).