I am embarrassed to admit it but I have figured out what I did wrong with these scans. After both the first scan which found one PUP and the later scan that found 108 PUPs, I clicked on the "remove this item", thinking that was all I had to do to be rid of them. But after reading daledoc1's message about removing detections, I realized that I had not checked the individual items so I ran the scan again, again finding 108 detections but this time I checked all of the items before clicking "remove items". I immediately rebooted and ran the scan again, this time finding NONE. I checked at C:\Windows\Temp\file_to_run551542.exe and it was GONE ! I feel like a dunce about this but perhaps it will alert a reader to a similar mistake. Incidentally, I also ran a full scan of Windows Defender and it found "no threats detected" Thanks for your help with this.